AACR Logo Assisted by ultrasound supervision, treating tumors with tremendous or moderate heat may offer a probable therapeutic alternative, as per a preliminary study.

Hyperthermia was said to be previously exhibited to augment radiation damage to cancerous tissue and avert following tissue repair. Apparently, it has further illustrated to improve chemotherapy and immunotherapy treatments by altering the microcirculation and blood vessel permeability properties of a tumor.

Osama M. Al-Bataineh, Ph.D., an assistant professor in biomedical engineering at the Hashemite University in Jordan, commented, “Low temperature controlled hyperthermia and high temperature treatments are beneficial in curing both malignant and benign tumors using minimally invasive and noninvasive ultrasound techniques.”

Al-Bataineh and colleagues supposedly conducted the following laboratory experiments. By means of magnetic resonance imaging (MRI) guidance, they could preserve preferred temperature levels of 43 degrees Celsius for around 30 minutes, which is believed to be the optimal dose to cause the necessary biological consequence for hyperthermia treatment.

In a connected experiment, high temperature more than 50 degrees Celsius for between one to two minutes appear to cause lasting tissue impairment to the prostate tumor. Elevated temperature treatment seemed to stimulate necrosis, or cell death.

Al-Bataineh mentioned that both extreme and moderate heat could encompass an obvious consequence on the tumor’s cellular structure, but additional studies may be required to be conducted prior to any studies being performed in humans.

The study was presented at the second AACR Dead Sea International Conference on Advances in Cancer Research: From the Laboratory to the Clinic.